Research Catalog

Title

Cytokines and the liver / edited by W. Gerok [and others].

Author

Falk Symposium (78th : 1994 : Freiburg im Breisgau, Germany)

Publication

Dordrecht ; Boston : Kluwer Academic Publishers, [1995], ©1995.

Items in the Library & Off-site

Details

Additional Authors

• Gastroenterology Week (1994 : Freiburg im Breisgau, Germany)
• Gerok, W. (Wolfgang), 1926-

Description

xii, 228 pages : illustrations; 25 cm.

Summary

• Cytokines are synthesized and secreted in the liver by Kupffer cells, and are important for inflammation processes, the non-specific immune response, and probably the destruction and removal of tumour cells. The production of signal substances such as tumour necrosis factor-[alpha], interleukin 1 and 6, and interferon [alpha]/[beta] is regulated by a complex set of pathways, which can also be modified by cellular mediators, e.g. prostaglandins, growth factors and corticosteroids.
• Signal exchange between different cell types in the liver is important for the synthesis of acute phase proteins, liver fibrosis, permeability and liver regeneration. This has clinical implications for hepatitis, cirrhosis and liver transplantation.
• This book is the proceedings of the 78th Falk Symposium (Part II of the Gastroenterology Week, Freiburg, 1994) held in Freiburg, Germany, on 15-16 June, 1994, and brings together clinicians and researchers worldwide to discuss the role of cytokines in hepatology.

Series Statement

Falk Symposium ; v.78

Uniform Title

Falk symposium (Series) ; 78.

Subjects

• Congress
• Liver > metabolism
• Receptors, Cytokine > physiology
• Cytokines > physiology
• Cytokines > Congresses
• Liver > Pathophysiology > Congresses
• Liver > Immunology > Congresses

Genre/Form

Congress.

Note

• "Proceedings of the 78th Falk Symposium (Part II of the Gastroenterology Week, Freiburg, 1994) held in Freiburg-im-Breisgau, Germany, June 15-16, 1994."
• "Falk Symposium 78."

Bibliography (note)

• Includes bibliographical references and index.

Contents

• 1. Interleukin-8 and other chemokines: new perspectives in inflammation / M. Baggiolini, M. Uguccioni and M. D'Apuzzo -- 2. IL-6 signal transduction from the plasma membrane to the nucleus / F. Horn, C. Lutticken, U. Wegenka, J. Yuan and P. C. Heinrich -- 3. Activation of NH-[kappa]B and AP-1 in rat Kupffer cells / T. A. Tran-thi, K. Decker and P. A. Baeuerle -- 4. Cytokines and adhesion molecules in the liver / K. Tanikawa -- 5. Role of sinusoidal endothelial cells in liver fibrosis / G. Ramadori and K. Neubauer -- 6. The contribution of hepatocytes to cytokine-directed activation of fat-storing cells - a pathogenetic key mechanism in liver fibrogenesis / A. M. Gressner, C. Hoffmann, M. G. Bachem, G. Schuftan, B. Lahmer and A. Brenzel -- 7. On the contraction and relaxation of stellate cells induced by Kupffer cell-derived vasoactive substances / N. Kawada and K. Decker --
• 8. The initiation of liver regeneration and the regulation of liver growth by transforming growth factor alpha (TGF-[alpha]) / N. Fausto -- 9. Role of HGF in liver regeneration / G. K. Michalopoulos, W. M. Mars and M.-L. Liu -- 10. Kupffer cell processing of bacterial lipopolysaccharide / E. S. Fox and P. Thomas -- 11. Cytokines in alcoholic liver cirrhosis / J. Deviere, O. le Moine, M. Goldman and E. Dupont -- 12. Autoimmune hepatitis and cytokines / C. Trautwein and M. P. Manns -- 13. Cytokine profiles in primary biliary cirrhosis: an approach to define the underlying immunoreactivity / P. A. Berg, R. Klein, M. Leuschner and U. Leuschner -- 14. Growth factors in liver disease / W. E. Fleig -- 15. Cytokine regulation of hepatic acute phase protein expression / Z. Xing, C. D. Richards, T. Braciak, V. Thibault and J. Gauldie -- 16. Cytokine-induced alterations in hepatic lipid metabolism / K. R. Feingold, I. Hardardottir and C. Grunfeld --
• 17. Cytokines in liver transplantation and alcoholic liver disease / R. G. Thurman, E. Savier, Y. Adachi, S. I. Shedlofsky, J. J. Lemasters, W. Gao, B. U. Bradford, Z. Zhong, K. T. Knecht, W. Qu, R. T. Currin, S. Lichtmman, J. Wang and M. Goto -- 18. Role of cytokines in the regulation of cell - cell and cell - matrix adhesion molecules in human liver transplants / G. Steinhoff -- 19. Cytokines in liver allograft rejection / A. S. Gaweco and W. J. Hofmann.

ISBN

079238878X (HB)

LCCN

95011356

Owning Institutions

Columbia University Libraries